小鼠抗JAK1单克隆抗体

Background:

This gene encodes a membrane protein that is a member of a class of protein-tyrosine kinases (PTK) characterized by the presence of a second phosphotransferase-related domain immediately N-terminal to the PTK domain. The encoded kinase phosphorylates STAT proteins (signal transducers and activators of transcription) and plays a key role in interferon-alpha/beta and interferon-gamma signal transduction. Alternative splicing results in multiple transcript variants.

Applications:

WB, IF, IP

Name of antibody:

JAK1

Immunogen:

Fusion protein of human JAK1

Full name:

Janus kinase 1

Synonyms:

JTK3; JAK1A; JAK1B

SwissProt:

P23458

WB Predicted band size:

133 kDa

WB Positive control:

C6, Ramos, Jurkat and Hela cell lysates

WB Recommended dilution:

1000-5000

IF positive control:

Hela cells

IF Recommend dilution:

100-200