中文名称 : 小鼠抗IL36G单克隆抗体
Background: |
The protein encoded by this gene is a member of the interleukin 1 cytokine family. The activity of this cytokine is mediated by interleukin 1 receptor-like 2 (IL1RL2/IL1R-rp2), and is specifically inhibited by interleukin 1 family, member 5 (IL1F5/IL-1 delta). Interferon-gamma, tumor necrosis factor-alpha and interleukin 1, beta (IL1B) are reported to stimulate the expression of this cytokine in keratinocytes. The expression of this cytokine in keratinocytes can also be induced by a contact hypersensitivity reaction or herpes simplex virus infection. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Applications: |
WB, IHC, IF |
Name of antibody: |
IL36G |
Immunogen: |
Fusion protein of human IL36G |
Full name: |
interleukin 36, gamma (IL36G), transcript variant 1 |
Synonyms: |
IL1E; IL1F9; IL1H1; IL-1F9; IL-1H1; IL1RP2; IL-1RP2 |
SwissProt: |
Q9NZH8 |
IHC positive control: |
human pancreas tissue and adenocarcinoma of human colon tissue |
IHC Recommend dilution: |
30-150 |
WB Predicted band size: |
19 kDa |
WB Positive control: |
MCF7 cell lysate |
WB Recommended dilution: |
200-1000 |