小鼠抗HSD17B8单克隆抗体

Background:

In mice, the Ke6 protein is a 17-beta-hydroxysteroid dehydrogenase that can regulate the concentration of biologically active estrogens and androgens. It is preferentially an oxidative enzyme and inactivates estradiol, testosterone, and dihydrotestosterone. However, the enzyme has some reductive activity and can synthesize estradiol from estrone. The protein encoded by this gene is similar to Ke6 and is a member of the short-chain dehydrogenase superfamily. An alternatively spliced transcript of this gene has been detected, but the full-length nature of this variant has not been determined. [provided by RefSeq, Jul 2008].

Applications:

WB, IHC

Name of antibody:

HSD17B8

Immunogen:

Fusion protein of human HSD17B8

Full name:

hydroxysteroid (17-beta) dehydrogenase 8 (HSD17B8)

Synonyms:

D6S2245E; dJ1033B10.9; FABG; FABGL; H2-KE6; HKE6; KE6; RING2; SDR30C1

SwissProt:

Q92506

IHC positive control:

carcinoma of human liver tissue

IHC Recommend dilution:

30-150

WB Predicted band size:

27 kDa

WB Positive control:

Hela, A549, MCF-7 cell lysates

WB Recommended dilution:

500-2000