小鼠抗HOXC11单克隆抗体

Background:

This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12. The product of this gene binds to a promoter element of the lactase-phlorizin hydrolase. It also may play a role in early intestinal development. An alternatively spliced variant encoding a shorter isoform has been described but its full-length nature has not been determined. [provided by RefSeq]. COMPLETENESS: complete on the 3' end.

Applications:

WB, IHC, IF, FC

Name of antibody:

HOXC11

Immunogen:

Fusion protein of human HOXC11

Full name:

homeobox C11 (HOXC11)

Synonyms:

HOX3H

SwissProt:

O43248

IHC positive control:

adenocarcinoma of human breast tissue and adenocarcinoma of human colon tissue; human endometrium tissue and carcinoma of human bladder tissue

IHC Recommend dilution:

30-150

WB Predicted band size:

34 kDa

WB Positive control:

Human testis tissue, Human omentum tissue, Human uterus tissue, Human breast tissue, Human liver tissue, Human ovarian tissue, Human thyroid gland tissue, Human colon tissue lysates

WB Recommended dilution:

500-2000