中文名称:小鼠抗HDAC8单克隆抗体
Background: |
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene. |
Applications: |
WB |
Name of antibody: |
HDAC8 |
Immunogen: |
Fusion protein of human HDAC8 |
Full name: |
histone deacetylase 8 |
Synonyms: |
HD8; WTS; RPD3; CDA07; CDLS5; MRXS6; HDACL1 |
SwissProt: |
Q9BY41 |
WB Predicted band size: |
42 KD |
WB Positive control: |
Hela, Molt4, K562, NIH/3T3, 293T and Jurkat cell lysates |
WB Recommended dilution: |
500-2000 |