中文名称:小鼠抗GRK2单克隆抗体
技术规格
Background: |
The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart. |
Applications: |
WB |
Name of antibody: |
GRK2 |
Immunogen: |
Fusion protein of human GRK2 |
Full name: |
G protein-coupled receptor kinase 2 |
Synonyms: |
BARK1; ADRBK1; BETA-ARK1 |
SwissProt: |
P25098 |
WB Predicted band size: |
80 kDa |
WB Positive control: |
THP-1 and Ramos cell lysates |
WB Recommended dilution: |
200-1000 |
