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中文名称：小鼠抗GPR151单克隆抗体
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Background: |
This gene encodes an orphan member of the class A rhodopsin-like family of G-protein-coupled receptors (GPCRs). Within the rhodopsin-like family, this gene is a member of the SOG subfamily that includes somatostatin, opioid, galanin, and kisspeptin receptors. The orthologous mouse gene has a restricted pattern of neuronal expression which is induced following nerve injury. All GPCRs have a transmembrane domain that includes seven transmembrane alpha-helices. A general feature of GPCR signaling is the agonist-induced conformational change in the receptor, leading to activation of the heterotrimeric G protein. The activated G protein then binds to and activates numerous downstream effector proteins, which generate second messengers that mediate a broad range of cellular and physiological processes. |
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Applications: |
WB |
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Name of antibody: |
GPR151 |
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Immunogen: |
Fusion protein of human GPR151 |
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Full name: |
G protein-coupled receptor 151 |
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Synonyms: |
GPCR; PGR7; GALR4; GALRL; GPCR-2037 |
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SwissProt: |
Q8TDV0 |
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WB Predicted band size: |
47 KD |
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WB Positive control: |
HUVEC cell lysate |
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WB Recommended dilution: |
500-2000 |
