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021-54845833/15800441009
中文名称：小鼠抗FTO单克隆抗体
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Background: |
This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes. |
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Applications: |
WB, IHC |
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Name of antibody: |
FTO |
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Immunogen: |
Fusion protein of human FTO |
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Full name: |
FTO, alpha-ketoglutarate dependent dioxygenase |
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Synonyms: |
GDFD; ALKBH9; BMIQ14 |
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SwissProt: |
Q9C0B1 |
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IHC positive control: |
Human breast tissue and Human ovarian cancer; Human pancreas tissue and Human endometrium tissue |
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IHC Recommend dilution: |
200-500 |
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WB Predicted band size: |
58 KD |
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WB Positive control: |
Jurkat, Hela, HepG2, 293T, SH-SY5Y cell lysates |
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WB Recommended dilution: |
500-2000 |
