小鼠抗FN1单克隆抗体

Background:

This gene encodes fibronectin, a glycoprotein present in a soluble dimeric form in plasma, and in a dimeric or multimeric form at the cell surface and in extracellular matrix. The encoded preproprotein is proteolytically processed to generate the mature protein. Fibronectin is involved in cell adhesion and migration processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis. The gene has three regions subject to alternative splicing, with the potential to produce 20 different transcript variants, at least one of which encodes an isoform that undergoes proteolytic processing. The full-length nature of some variants has not been determined.

Applications:

WB

Name of antibody:

FN1

Immunogen:

Fusion protein of human FN1

Full name:

fibronectin 1

Synonyms:

FN; CIG; FNZ; MSF; ED-B; FINC; GFND; LETS; GFND2; SMDCF

SwissProt:

P02751

WB Predicted band size:

272 kDa

WB Positive control:

Human breast tissue, Human plasma solution

WB Recommended dilution:

1000-5000