小鼠抗ERCC4单克隆抗体

Background:

The protein encoded by this gene forms a complex with ERCC1 and is involved in the 5' incision made during nucleotide excision repair. This complex is a structure specific DNA repair endonuclease that interacts with EME1. Defects in this gene are a cause of xeroderma pigmentosum complementation group F (XP-F), or xeroderma pigmentosum VI (XP6).

Applications:

WB, IHC, IF, FC

Name of antibody:

ERCC4

Immunogen:

Fusion protein of human ERCC4

Full name:

excision repair cross-complementation group 4 (ERCC4)

Synonyms:

XPF; RAD1; FANCQ; XFEPS; ERCC11

SwissProt:

Q92889

IHC positive control:

adenocarcinoma of human breast tissue and human kidney tissue; carcinoma of human liver tissue and carcinoma of human lung tissue

IHC Recommend dilution:

30-150

WB Predicted band size:

104 kDa

WB Positive control:

HepG2, SVT2, A549, COS7, Jurkat, MCF-7 cell lysates

WB Recommended dilution:

500-2000