中文名称 : 小鼠抗ENG单克隆抗体
Background: |
This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds TGFB1 and TGFB3 with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]. |
Applications: |
WB, IF |
Name of antibody: |
ENG |
Immunogen: |
Fusion protein of human ENG |
Full name: |
endoglin (ENG), transcript variant 2 |
Synonyms: |
END; HHT1; ORW1 |
SwissProt: |
P17813 |
WB Predicted band size: |
71 kDa |
WB Positive control: |
HepG2, Hela, SVT2, A549, COS7, Jurkat, MDCK, PC12, MCF-7 cell lysates |
WB Recommended dilution: |
500-2000 |