小鼠抗DTNB单克隆抗体

Background:

This gene encodes dystrobrevin beta, a component of the dystrophin-associated protein complex (DPC). The DPC consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and dystrobrevin alpha and beta. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Dystrobrevin beta is thought to interact with syntrophin and the DP71 short form of dystrophin. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq].

Applications:

WB, IF, FC

Name of antibody:

DTNB

Immunogen:

Fusion protein of human DTNB

Full name:

dystrobrevin, beta (DTNB), transcript variant 5

Synonyms:

MGC17163; MGC57126

SwissProt:

O60941

WB Predicted band size:

71 kDa

WB Positive control:

HepG2, Hela, SVT2, COS7, PC12, MCF-7 cell lysates

WB Recommended dilution:

200-1000