中文名称:小鼠抗DPYSL2单克隆抗体
Background: |
This gene encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological disorders, and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimer's disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
Applications: |
WB |
Name of antibody: |
DPYSL2 |
Immunogen: |
Fusion protein of human DPYSL2 |
Full name: |
dihydropyrimidinase like 2 |
Synonyms: |
DRP2; N2A3; CRMP2; DRP-2; ULIP2; CRMP-2; DHPRP2; ULIP-2 |
SwissProt: |
Q16555 |
WB Predicted band size: |
62 KD |
WB Positive control: |
PC12, U87, NIH/3T3 cell lysates |
WB Recommended dilution: |
500-2000 |