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中文名称： ZBTB20 抗原（重组蛋白）
英文名称： ZBTB20 Antigen (Recombinant Protein)
别 名： zinc finger and BTB domain containing 20; HOF; DPZF; PRIMS; ODA-8S; ZNF288
储 存： 冷冻（-20℃）
相关类别：抗原
概 述
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Full name: |
zinc finger and BTB domain containing 20 |
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Synonyms: |
HOF; DPZF; PRIMS; ODA-8S; ZNF288 |
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Swissprot: |
Q9HC78 |
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Gene Accession: |
BC029041 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene, which was initially designated as dendritic cell-derived BTB/POZ zinc finger (DPZF), belongs to a family of transcription factors with an N-terminal BTB/POZ domain and a C-terminal DNA-bindng zinc finger domain. The BTB/POZ domain is a hydrophobic region of approximately 120 aa which mediates association with other BTB/POZ domain-containing proteins. This gene acts as a transcriptional repressor and plays a role in many processes including neurogenesis, glucose homeostasis, and postnatal growth. Mutations in this gene have been associated with Primrose syndrome as well as the 3q13.31 microdeletion syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms. |
