中文名称 : 小鼠抗CBX8单克隆抗体
Background: |
Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. |
Applications: |
WB, IHC |
Name of antibody: |
CBX8 |
Immunogen: |
Fusion protein of human CBX8 |
Full name: |
chromobox homolog 8 (CBX8) |
Synonyms: |
PC3; RC1 |
SwissProt: |
Q9HC52 |
IHC positive control: |
carcinoma of human thyroid tissue |
IHC Recommend dilution: |
25-100 |
WB Predicted band size: |
43 kDa |
WB Positive control: |
HepG2, Hela, SVT2, A549, COS7, Jurkat, MDCK, PC12, MCF-7 cell lysates |
WB Recommended dilution: |
1000-5000 |