中文名称 : 小鼠抗BID单克隆抗体
Background: |
This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined. [provided by RefSeq, Jul 2008]. |
Applications: |
WB, IHC, IF |
Name of antibody: |
BID |
Immunogen: |
Fusion protein of human BID |
Full name: |
BH3 interacting domain death agonist (BID), transcript variant 2 |
Synonyms: |
FP497 |
SwissProt: |
P55957 |
IHC positive control: |
human pancreas tissue and adenocarcinoma of human endometrium tissue; human liver tissue and carcinoma of human liver tissue |
IHC Recommend dilution: |
30-150 |
WB Predicted band size: |
22 kDa |
WB Positive control: |
HepG2, Hela, A549, Jurkat, MCF-7 cell lysates |
WB Recommended dilution: |
500-2000 |