中文名称 : 小鼠抗ATRIP单克隆抗体
Background: |
The product of this gene is an essential component of the DNA damage checkpoint, and binds to single-stranded DNA coated with replication protein A that accumulates at sites of DNA damage. The encoded protein interacts with the ataxia telangiectasia and Rad3 related protein, a checkpoint kinase, resulting in accumulation of the kinase at intranuclear foci induced by DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]. |
Applications: |
WB, IHC, IF, FC |
Name of antibody: |
ATRIP |
Immunogen: |
Fusion protein of human ATRIP |
Full name: |
ATR interacting protein (ATRIP), transcript variant 1 |
Synonyms: |
DKFZp762J2115; FLJ12343; MGC20625; MGC21482; MGC26740 |
SwissProt: |
Q8WXE1 |
IHC positive control: |
adenocarcinoma of human ovary tissue and adenocarcinoma of human endometrium tissue; human kidney tissue and human pancreas tissue |
IHC Recommend dilution: |
30-150 |
WB Predicted band size: |
86 kDa |
WB Positive control: |
HepG2, Hela, SVT2, A549, Jurkat, MDCK, PC12, MCF-7 cell lysates |
WB Recommended dilution: |
500-2000 |