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021-54845833/15800441009
中文名称：小鼠抗ATP6V1B2单克隆抗体
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Background: |
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. The protein encoded by this gene is one of two V1 domain B subunit isoforms and is the only B isoform highly expressed in osteoclasts. [provided by RefSeq, Jul 2008]. |
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Applications: |
WB, IHC |
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Name of antibody: |
ATP6V1B2 |
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Immunogen: |
Fusion protein of human ATP6V1B2 |
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Full name: |
ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 (ATP6V1B2) |
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Synonyms: |
HO57; VATB; VPP3; Vma2; ATP6B2; ATP6B1B2 |
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SwissProt: |
P21281 |
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IHC positive control: |
human breast tissue and carcinoma of human liver tissue; adenocarcinoma of human ovary tissue and adenocarcinoma of human breast tissue |
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IHC Recommend dilution: |
30-150 |
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WB Predicted band size: |
57 kDa |
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WB Positive control: |
HepG2, Hela, SVT2, A549, COS7, Jurkat, MDCK, PC12, MCF-7 cell lysates |
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WB Recommended dilution: |
500-2000 |
