中文名称 : 小鼠抗ATIC单克隆抗体
Background: |
This gene encodes a bifunctional protein that catalyzes the last two steps of the de novo purine biosynthetic pathway. The N-terminal domain has phosphoribosylaminoimidazolecarboxamide formyltransferase activity, and the C-terminal domain has IMP cyclohydrolase activity. A mutation in this gene results in AICA-ribosiduria. [provided by RefSeq]. |
Applications: |
WB, FC |
Name of antibody: |
ATIC |
Immunogen: |
Fusion protein of human ATIC |
Full name: |
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase (ATIC) |
Synonyms: |
AICAR; AICARFT; HEL-S-70p; IMPCHASE; PURH |
SwissProt: |
P31939 |
WB Predicted band size: |
65 kDa |
WB Positive control: |
HepG2, Hela, SVT2, A549, COS7, MDCK, PC12, MCF-7 cell lysates |
WB Recommended dilution: |
500-2000 |