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中文名称： USP14 抗原（重组蛋白）
英文名称： USP14 Antigen (Recombinant Protein)
别 名： ubiquitin specific peptidase 14; TGT
相关类别：抗原
储 存： 冷冻（-20℃）
概 述
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Full name: |
ubiquitin specific peptidase 14 |
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Synonyms: |
TGT |
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Swissprot: |
P54578 |
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Gene Accession: |
BC003556 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes a member of the ubiquitin-specific processing (UBP) family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the cytoplasm and cleaves the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins. Mice with a mutation that results in reduced expression of the ortholog of this protein are retarded for growth, develop severe tremors by 2 to 3 weeks of age followed by hindlimb paralysis and death by 6 to 10 weeks of age. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. |
