中文名称 : 小鼠抗ATG4B单克隆抗体
Background: |
Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. |
Applications: |
WB, IHC |
Name of antibody: |
ATG4B |
Immunogen: |
Fusion protein of human ATG4B |
Full name: |
autophagy related 4B cysteine peptidase |
Synonyms: |
APG4B; AUTL1 |
SwissProt: |
Q9Y4P1 |
IHC positive control: |
Human endometrial cancer |
IHC Recommend dilution: |
500-2000 |
WB Predicted band size: |
44 KD |
WB Positive control: |
Ramos, 293T, Jurkat, Hela, COLO205, U251, PC3 cell lysates |
WB Recommended dilution: |
500-2000 |