中文名称:小鼠抗AMACR单克隆抗体
Background: |
This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene. |
Applications: |
WB |
Name of antibody: |
AMACR |
Immunogen: |
Fusion protein of human AMACR |
Full name: |
alpha-methylacyl-CoA racemase |
Synonyms: |
RM; RACE; CBAS4; P504S; AMACRD |
SwissProt: |
Q9UHK6 |
WB Predicted band size: |
42 kDa |
WB Positive control: |
PC3, LNCAP, Hela, HepG2 cell, Mouse kidney tissue, Mouse liver tissue lysates |
WB Recommended dilution: |
1000-5000 |