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中文名称： 兔抗ADAM15多克隆抗体
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Background: |
The protein encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
ADAM15 |
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Immunogen: |
Fusion protein of human ADAM15 |
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Full name: |
ADAM metallopeptidase domain 15 |
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Synonyms: |
MDC15 |
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SwissProt: |
Q13444 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human tonsil and Human prostate cancer |
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IHC Recommend dilution: |
50-200 |
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WB Predicted band size: |
93 kDa |
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WB Positive control: |
Jurkat, PC-3, HepG2 and NIH/3T3 cell lysates |
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WB Recommended dilution: |
500-2000 |
