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中文名称：小鼠抗ACTA1单克隆抗体
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Background: |
The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause a variety of myopathies, including nemaline myopathy, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects with manifestations such as hypotonia. |
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Applications: |
WB |
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Name of antibody: |
ACTA1 |
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Immunogen: |
Fusion protein of human ACTA1 |
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Full name: |
actin alpha 1, skeletal muscle |
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Synonyms: |
ACTA; ASMA; CFTD; MPFD; NEM1; NEM2; NEM3; SHPM; CFTD1; CFTDM |
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SwissProt: |
P68133 |
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WB Predicted band size: |
42 kDa |
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WB Positive control: |
Mouse brain tissue, Human cerebrum tissue, Human cerebella tissue lysates |
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WB Recommended dilution: |
1000-5000 |
