兔抗CFH多克隆抗体

Background:

This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short consensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Applications:

ELISA, WB

Name of antibody:

CFH

Immunogen:

Synthetic peptide of human CFH

Full name:

complement factor H

Synonyms:

FH; HF; HF1; HF2; HUS; FHL1; AHUS1; AMBP1; ARMD4; ARMS1; CFHL3

SwissProt:

P08603

ELISA Recommended dilution:

5000-10000

WB Predicted band size:

139 kDa

WB Positive control:

Human plasma solution

WB Recommended dilution:

200-1000