兔抗ZNHIT1多克隆抗体

Background:

ZNHIT1 (zinc finger, HIT-type containing 1), also known as CG1I (cyclin-G1-binding protein 1), p18 hamlet or ZNFN4A1 (zinc finger protein subfamily 4A member 1), is a 154 amino acid protein that plays a role in the induction of p53-mediated apoptosis. A member of the ZNHIT1 family, ZNHIT1 contains one HIT-type zinc finger and interacts with p38. ZNHIT1 undergoes post-translational phosphorylation and is encoded by a gene that maps to human chromosome 7, which houses over 1,000 genes and comprises nearly 5% of the human genome. Chromosome 7 has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. The deletion of a portion of the q arm of chromosome 7 is associated with Williams-Beuren syndrome, a condition characterized by mild mental retardation, an unusual comfort and friendliness with strangers and an elfin appearance.

Applications:

ELISA, IHC

Name of antibody:

ZNHIT1

Immunogen:

Full length fusion protein

Full name:

zinc finger HIT-type containing 1

Synonyms:

CG1I; ZNFN4A1

SwissProt:

O43257

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human thyroid cancer and human esophagus cancer

IHC Recommend dilution:

25-100