中文名称:兔抗CDK14多克隆抗体
英文名称: Anti-CDK14 rabbit polyclonal antibody
别 名: PFTK1; PFTAIRE1
相关类别: 一抗
储 存: 冷冻(-20℃)
宿 主: Rabbit
抗 原: CDK14
反应种属: Human, Mouse
标 记 物: Unconjugate
克隆类型: rabbit polyclonal
技术规格
Background: |
Serine/threonine-protein kinase involved in the control of the eukaryotic cell cycle, whose activity is controlled by an associated cyclin. Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by mediating the phosphorylation of LRP6 at 'Ser-1490', leading to the activation of the Wnt signaling pathway. Acts as a regulator of cell cycle progression and cell proliferation via its interaction with CCDN3. Phosphorylates RB1 in vitro, however the relevance of such result remains to be confirmed in vivo. May also play a role in meiosis, neuron differentiation and may indirectly act as a negative regulator of insulin-responsive glucose transport. |
Applications: |
ELISA, WB, IHC |
Name of antibody: |
CDK14 |
Immunogen: |
Synthetic peptide of human CDK14 |
Full name: |
cyclin-dependent kinase 14 |
Synonyms: |
PFTK1; PFTAIRE1 |
SwissProt: |
O94921 |
ELISA Recommended dilution: |
5000-10000 |
IHC positive control: |
Human liver cancer |
IHC Recommend dilution: |
20-100 |
WB Predicted band size: |
53 kDa |
WB Positive control: |
Mouse Pancreas tissue lysate |
WB Recommended dilution: |
200-1000 |