兔抗CDK2多克隆抗体

Background:

The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein kinase is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and essential for cell cycle G1/S phase transition. This protein associates with and regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Its activity is also regulated by its protein phosphorylation. Two alternatively spliced variants and multiple transcription initiation sites of this gene have been reported.

Applications:

ELISA, WB, IHC

Name of antibody:

CDK2

Immunogen:

Fusion protein of human CDK2

Full name:

cyclin-dependent kinase 2

Synonyms：

p33(CDK2)

SwissProt:

P24941

ELISA Recommended dilution:

1000-2000

IHC positive control:

Human cervical cancer

IHC Recommend dilution:

15-50

WB Predicted band size:

34 kDa

WB Positive control:

A431 and 231 cells, hela cells and human fetal liver tissue

WB Recommended dilution:

200-1000