中文名称:兔抗ZKSCAN3多克隆抗体
Background: |
Transcriptional factor that binds to the consensus sequence 5'-[GT][AG][AGT]GGGG-3' and acts as a repressor of autophagy. Specifically represses expression of genes involved in autophagy and lysosome biogenesis/function such as MAP1LC3B, ULK1 or WIPI2. Associates with chromatin at the ITGB4 and VEGF promoters. Also acts as a transcription activator and promotes cancer cell progression and/or migation in various tumors and myelomas. |
Applications: |
ELISA, IHC |
Name of antibody: |
ZKSCAN3 |
Immunogen: |
Fusion protein of human ZKSCAN3 |
Full name: |
zinc finger with KRAB and SCAN domains 3 |
Synonyms: |
ZF47; Zfp47; ZFP306; ZNF306; ZNF309; zfp-47; ZSCAN13; ZSCAN35; dJ874C20.1; dJ874C20.1. |
SwissProt: |
Q9BRR0 |
ELISA Recommended dilution: |
5000-10000 |
IHC positive control: |
Human gastric cancer |
IHC Recommend dilution: |
25-100 |