兔抗CD163多克隆抗体

Background:

The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Applications:

ELISA, IHC

Name of antibody:

CD163

Immunogen:

Synthetic peptide of human CD163

Full name:

CD163 molecule

Synonyms:

M130; MM130

SwissProt:

Q86VB7

IHC positive control:

Human gastric cancer and human thyroid cancer

IHC Recommend dilution:

25-100