兔抗ZAK多克隆抗体

Background:

This gene is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM). This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells. The protein also has pro-apoptotic activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Applications:

WB, IF

Name of antibody:

ZAK

Immunogen:

Synthesized peptide derived from C-terminal of human MLTK.

Full name:

sterile alpha motif and leucine zipper containing kinase AZK

Synonyms：

pk; AZK; MLT; MRK; MLK7; MLTK; mlklak

SwissProt:

Q9NYL2

WB Predicted band size:

91 kDa

WB Positive control:

Hela cells lysate

WB Recommended dilution:

500-3000

IF positive control:

HepG2 cells

IF Recommend dilution:

100-500