兔抗CD86多克隆抗体

Background:

This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.

Applications:

ELISA, IHC

Name of antibody:

CD86

Immunogen:

Fusion protein of human CD86

Full name:

CD86 molecule

Synonyms:

B70; B7-2; B7.2; LAB72; CD28LG2

SwissProt:

P42081

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human gastric cancer

IHC Recommend dilution:

40-200