兔抗YWHAQ多克隆抗体

Background:

This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease.

Applications:

ELISA, WB, IHC

Name of antibody:

YWHAQ

Immunogen:

Synthetic peptide of human YWHAQ

Full name:

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide

Synonyms：

1C5, HS1, 14-3-3

SwissProt:

P27348

ELISA Recommended dilution:

2000-10000

IHC positive control:

Human ovarian cancer and Human lung cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

28 kDa

WB Positive control:

Mouse brain tissue, A549 cells and human lymphoma tissue, hela cells

WB Recommended dilution:

1000-5000