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021-54845833/15800441009
中文名称： 兔抗YTHDF1多克隆抗体
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Background: |
YTHDF1, also designated Dermatomyositis associated with cancer putative autoantigen 1 (DACA-1), is a 559 amino acid protein that contains one YTH domain, which is a potential RNA binding domain. Specifically recognizes and binds N6-methyladenosine (m6A)-containing mRNAs, and promotes mRNA translation efficiency (PubMed:24284625, PubMed:26046440, PubMed:26318451). M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in the efficiency of mRNA splicing, processing and stability (PubMed:24284625). Acts as a regulator of mRNA translation efficiency: promotes ribosome loading to m6A-containing mRNAs and interacts with translation initiation factors eIF3 (EIF3A or EIF3B) to facilitate translation initiation (PubMed:26046440). |
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Applications: |
ELISA, IHC |
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Name of antibody: |
YTHDF1 |
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Immunogen: |
Synthetic peptide of human YTHDF1 |
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Full name: |
YTH N6-methyladenosine RNA binding protein 1 |
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Synonyms: |
C20orf21 |
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SwissProt: |
Q9BYJ9 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human cervical cancer |
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IHC Recommend dilution: |
40-200 |
