中文名称:兔抗XRN1多克隆抗体
Background: |
This gene encodes a member of the 5'-3' exonuclease family. The encoded protein may be involved in replication-dependent histone mRNA degradation, and interacts directly with the enhancer of mRNA-decapping protein 4. In addition to mRNA metabolism, a similar protein in yeast has been implicated in a variety of nuclear and cytoplasmic functions, including homologous recombination, meiosis, telomere maintenance, and microtubule assembly. Mutations in this gene are associated with osteosarcoma, suggesting that the encoded protein may also play a role in bone formation. Alternative splicing results in multiple transcript variants. |
Applications: |
ELISA, WB, IHC |
Name of antibody: |
XRN1 |
Immunogen: |
Synthetic peptide of human XRN1 |
Full name: |
5'-3' exoribonuclease 1 |
Synonyms: |
SEP1 |
SwissProt: |
Q8IZH2 |
ELISA Recommended dilution: |
5000-10000 |
IHC positive control: |
Human esophagus cancer and human lung cancer |
IHC Recommend dilution: |
10-50 |
WB Predicted band size: |
194 kDa |
WB Positive control: |
Hela,231 and K562 cell lysates |
WB Recommended dilution: |
500-2000 |