中文名称:兔抗XRCC3多克隆抗体
Background: |
This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene functionally complements Chinese hamster irs1SF, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents and is chromosomally unstable. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. |
Applications: |
WB, IHC |
Name of antibody: |
XRCC3 |
Immunogen: |
Synthesized peptide derived from Internal of human XRCC3. |
Full name: |
X-ray repair complementing defective repair in Chinese hamster cells 3 |
Synonyms: |
CMM6 |
SwissProt: |
O43542 |
IHC positive control: |
Human lung carcinoma tissue |
IHC Recommend dilution: |
50-100 |
WB Predicted band size: |
38 kDa |
WB Positive control: |
HepG2 cells treated with Adriamycin (0.5uM, 5hours) lysate |
WB Recommended dilution: |
500-3000 |