中文名称: SERPINB4 抗原(重组蛋白)
英文名称: SERPINB4 Antigen (Recombinant Protein)
别 名: serpin family B member 4; PI11; SCCA1; SCCA2; LEUPIN; SCCA-2
储 存: 冷冻(-20℃)
相关类别:抗原
概 述
技术规格
Full name: |
serpin family B member 4 |
Synonyms: |
PI11; SCCA1; SCCA2; LEUPIN; SCCA-2 |
Swissprot: |
P48594 |
Gene Accession: |
BC017401 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
The protein encoded by this gene is a member of the serpin family of serine protease inhibitors. The encoded protein is highly expressed in many tumor cells and can inactivate granzyme M, an enzyme that kills tumor cells. This protein, along with serpin B3, can be processed into smaller fragments that aggregate to form an autoantigen in psoriasis, probably by causing chronic inflammation. |