英文名称: Anti-CCP110 rabbit polyclonal antibody
别 名: CP110; Cep110
相关类别: 一抗
储 存: 冷冻(-20℃)
克隆类型: rabbit polyclonal
技术规格
Background: |
Necessary for centrosome duplication at different stages of procentriole formation. Acts as a key negative regulator of ciliogenesis in collaboration with CEP97 by capping the mother centriole thereby preventing cilia formation (PubMed:17719545 PubMed:17681131, PubMed:23486064). Also involved in promoting ciliogenesis. May play a role in the assembly of the mother centriole subdistal appendages (SDA) thereby effecting the fusion of recycling endosomes to basal bodies during cilia formation (By similarity). Required for correct spindle formation and has a role in regulating cytokinesis and genome stability via cooperation with CALM1 and CETN2 (PubMed:16760425). |
Applications: |
ELISA, IHC |
Name of antibody: |
CCP110 |
Immunogen: |
Synthetic peptide corresponding to a region derived from 578-591 amino acids of human CCP110 |
Full name: |
centriolar coiled-coil protein 110 |
Synonyms: |
CP110; Cep110 |
SwissProt: |
O43303 |
ELISA Recommended dilution: |
5000-10000 |
IHC Positive control: |
Human brain; |
IHC Recommended dilution: |
10-50 |