Background: |
Xenotropic mouse leukemia viruses (X-MLVs) are broadly infectious for mammals except most of the classical strains of laboratory mice. These gammaretroviruses rely on the XPR1 receptor for entry, and the unique resistance of laboratory mice is due to two mutations in different putative XPR1extracellular loops. Cells from avian species differ in susceptibility to X-MLVs, and 2 replacement mutations in the virus-resistant chicken XPR1 distinguish it from the more permissive duck and quail receptors. |
Applications: |
ELISA, IHC |
Name of antibody: |
XPR1 |
Immunogen: |
Synthetic peptide of human XPR1 |
Full name: |
xenotropic and polytropic retrovirus receptor 1 |
Synonyms: |
X3; SYG1 |
SwissProt: |
Q9UBH6 |
ELISA Recommended dilution: |
1000-5000 |
IHC positive control: |
Human ovarian cancer and human gastric cancer |
IHC Recommend dilution: |
50-200 |