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021-54845833/15800441009
免抗CRP多克隆抗体
Package : 25 μl/100 μl/200 μl
Package : 25 μl/100 μl/200 μl
Storage : -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Ig class : Immunogen-specific rabbit IgG
Product : overview
Content : 0.8 mg/ml
Reactivity : Human, Mouse
Description : A nti-CRP rabbit polyclonal antibody
Applications : ELISA, WB, IHC
Immunogen : Fusion protein of human CRP
Host species : Rabbit
Purification : Antigen affinity purification
Target information
Symbol : CRP
Full name : C-reactive protein
Synonyms : PTX1
Swissprot : P02741
Target Background
The protein encoded by this gene belongs to the pentraxin family which also includes serum amyloid P component
protein and pentraxin 3. Pentraxins are involved in complement activation and amplification via communication with
complement initiation pattern recognition molecules, but also complement regulation via recruitment of complement
regulators. The encoded protein has a calcium dependent ligand binding domain with a distinctive flattened beta-jellyroll
structure. It exists in two forms as either a pentamer in circulation or as a nonsoluble monomer in tissues. It is involved in
several host defense related functions based on its ability to recognize foreign pathogens and damaged cells of the host
and to initiate their elimination by interacting with humoral and cellular effector systems in the blood. Consequently, the
level of this protein in plasma increases greatly during acute phase response to tissue injury, infection, or other
inflammatory stimuli. Elevated expression of the encoded protein is associated with severe acute respiratory syndrome
coronavirus 2 (SARS-CSoV-2) infection.
