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中文名称： RNF14 抗原（重组蛋白）
英文名称： RNF14 Antigen (Recombinant Protein)
别 名： ring finger protein 14; ARA54; HFB30; TRIAD2; HRIHFB2038
相关类别：抗原
技术规格
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Full name: |
ring finger protein 14 |
|
Synonyms: |
ARA54; HFB30; TRIAD2; HRIHFB2038 |
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Swissprot: |
Q9UBS8 |
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Gene Accession: |
BC126185 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein interacts with androgen receptor (AR) and may function as a coactivator that induces AR target gene expression in prostate. A dominant negative mutant of this gene has been demonstrated to inhibit the AR-mediated growth of prostate cancer. This protein also interacts with class III ubiquitin-conjugating enzymes (E2s) and may act as a ubiquitin-ligase (E3) in the ubiquitination of certain nuclear proteins. |
