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中文名称： RHOH抗原（重组蛋白）
英文名称： RHOH Antigen (Recombinant Protein)
别 名： TTF; ARHH
储 存： 冷冻（-20℃）
相关类别：抗原
概 述
技术规格
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Full name: |
ras homolog family member H |
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Synonyms: |
TTF; ARHH |
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Swissprot: |
Q15669 |
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Gene Accession: |
BC014261 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
The protein encoded by this gene is a member of the Ras superfamily of guanosine triphosphate (GTP)-metabolizing enzymes. The encoded protein is expressed in hematopoietic cells, where it functions as a negative regulator of cell growth and survival. This gene may be hypermutated or misexpressed in leukemias and lymphomas. Chromosomal translocations in non-Hodgkin's lymphoma occur between this locus and B-cell CLL/lymphoma 6 (BCL6) on chromosome 3, leading to the production of fusion transcripts. Alternative splicing in the 5' untranslated region results in multiple transcript variants that encode the same protein. |
