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中文名称： RGS1 抗原（重组蛋白）
英文名称： RGS1 Antigen (Recombinant Protein)
别 名： regulator of G-protein signaling 1; 1R20; BL34; IER1; IR20; HEL-S-87
储 存： 冷冻（-20℃）
相关类别：抗原
概 述
技术规格
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Full name: |
regulator of G-protein signaling 1 |
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Synonyms: |
1R20; BL34; IER1; IR20; HEL-S-87 |
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Swissprot: |
Q08116 |
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Gene Accession: |
BC015510 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes a member of the regulator of G-protein signalling family. This protein is located on the cytosolic side of the plasma membrane and contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signalling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. |
