兔抗CBX3(Phospho-Ser93)多克隆抗体

Background:

At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene.[provided by RefSeq, Mar 2011]

Applications:

WB

Name of antibody:

CBX3(Phospho-Ser93)

Immunogen:

Peptide sequence around phosphorylation site of Serine 93(R-L-S(p)-L-S) derived from Human HP1γ .

Full name:

chromobox homolog 3

Synonyms：

HECH; HP1-GAMMA; HP1Hs-gamma

SwissProt:

Q13185

WB Predicted band size:

21 kDa

WB Positive control:

K562 cells lysates treated with forskolin

WB Recommended dilution:

500-1000