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021-54845833/15800441009
中文名称：CHRNA3抗原
英文名称：CHRNA3 Antigen
别 名： LNCR2, PAOD2, NACHRA3
相关类别：抗原
储 存： 冷冻（-20℃）
概 述
技术规格
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Full name: |
cholinergic receptor, nicotinic, alpha 3 (neuronal) |
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Synonyms: |
LNCR2, PAOD2, NACHRA3 |
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Gene Accession: |
NP_000734 |
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SwissProt: |
P32297 |
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Background: |
This locus encodes a member of the nicotinic acetylcholine receptor family of proteins. Members of this family of proteins form pentameric complexes comprised of both alpha and beta subunits. This locus encodes an alpha-type subunit, as it contains characteristic adjacent cysteine residues. The encoded protein is a ligand-gated ion channel that likely plays a role in neurotransmission. Polymorphisms in this gene have been associated with an increased risk of smoking initiation and an increased susceptibility to lung cancer. Alternatively spliced transcript variants have been described. |
