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  • CDC23 抗原(重组蛋白)

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    • 目录号 : TW4202
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中文名称:CDC23 抗原(重组蛋白)

英文名称:CDC23 Antigen (Recombinant Protein)

别    名: cell division cycle 23; APC8; CUT23; ANAPC8

储    存: 冷冻(-20℃)

相关类别:抗原

概    述

Fusion protein corresponding to a region derived from 398-597 amino acids of human CDC23

技术规格

Full name:

cell division cycle 23

Synonyms:

APC8; CUT23; ANAPC8

Swissprot:

Q9UJX2

Gene Accession:

BC017713

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2/M transition. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eukaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction.