兔抗CAPNS1多克隆抗体

Background:

Calpains are a ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. Calpain families have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. Calpain I and II are heterodimeric with distinct large subunits associated with common small subunits, all of which are encoded by different genes. This gene encodes a small subunit common to both calpain I and II and is associated with myotonic dystrophy. Two transcript variants encoding the same protein have been identified for this gene.

Applications:

ELISA, WB, IHC

Name of antibody:

CAPNS1

Immunogen:

Fusion protein of human CAPNS1

Full name:

calpain, small subunit 1

Synonyms：

30K, CANP, CDPS, CSS1, CANPS, CAPN4, CALPAIN4

SwissProt:

P04632

ELISA Recommended dilution:

1000-2000

IHC positive control:

Human colon cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

28 kDa

WB Positive control:

Mouse spleen tissue, K562 and NIH/3T3 cells

WB Recommended dilution:

200-1000