兔抗CAPN9多克隆抗体

Background:

Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The protein encoded by this gene is expressed predominantly in stomach and small intestine and may have specialized functions in the digestive tract. This gene is thought to be associated with gastric cancer. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Applications:

ELISA, IHC

Name of antibody:

CAPN9

Immunogen:

Synthetic peptide of human CAPN9

Full name:

calpain 9

Synonyms:

GC36; nCL-4

SwissProt:

O14815

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human brain

IHC Recommend dilution:

25-100