兔抗CADM4多克隆抗体

Background:

IGSF4C (immunoglobulin superfamily member 4C), also known as CADM4 (cell adhesion molecule 4), NECL4 or TSLL2, is a 388 amino acid single-pass type I membrane protein that contains one Ig-like V-type domain and two Ig-like C2-type domains. Expressed in kidney, brain and prostate, IGSF4C exists as both a monomer and a homodimer and is thought to be involved in cell-cell adhesion, possibly playing a role in tumor suppression. Human IGSF4C shares 98% sequence identity with its mouse counterpart, suggesting a conserved role between species. The gene encoding IGSF4C maps to human chromosome 19, which is the genetic home for a number of immunoglobulin superfamily members, including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family and Fc receptors (FcRs)

Applications:

ELISA, WB, IHC

Name of antibody:

CADM4

Immunogen:

Synthetic peptide of human CADM4

Full name:

cell adhesion molecule 4

Synonyms：

NECL4; TSLL2; IGSF4C; Necl-4; synCAM4

SwissProt:

Q8NFZ8

ELISA Recommended dilution:

1000-2000

IHC positive control:

Human liver cancer and Human ovarian cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

43 kDa

WB Positive control:

RAW264.7 cells and mouse brain tissue

WB Recommended dilution:

200-1000