兔抗CACNA1H多克隆抗体

Background:

This gene encodes a T-type member of the alpha-1 subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. The alpha-1 subunit has 24 transmembrane segments and forms the pore through which ions pass into the cell. There are multiple isoforms of each of the proteins in the complex, either encoded by different genes or the result of alternative splicing of transcripts. Alternate transcriptional splice variants, encoding different isoforms, have been characterized for the gene described here. Studies suggest certain mutations in this gene lead to childhood absence epilepsy (CAE).

Applications:

WB

Name of antibody:

CACNA1H

Immunogen:

Synthesized peptide derived from internal of human CACNA1H.

Full name:

calcium channel, voltage-dependent, T type, alpha 1H subunit

Synonyms：

ECA6; EIG6; Cav3.2; CACNA1HB

SwissProt:

O95180

WB Predicted band size:

259 kDa

WB Positive control:

A549 cells lysate

WB Recommended dilution:

500-3000